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By: Nicksmith
Smooth muscle antibodies are great way to remove diseases. Some simple ailments such as allergic airway illnesses such as allergic rhinitis and asthma are characterized by local muscle damage and organ dysfunction within the upper and reduced respiratory tract arising from an abnormal hypersensitivity immune response to usually harmless and ubiquitous environmental allergens. Allergens that cause airway disease are predominantly seasonal tree, grass, and weed pollens or perennial inhalants such as (home dust mite antigen, cockroach, mold, animal dander, and some occupational protein antigens).

The clinical presentation of sensitized rhinitis includes nasal, ocular, and palatal pruritus, paroxysmal sneezing, rhinorrhea, and nasal congestion. A individual or family history of other allergic illnesses such as asthma or atopic dermatitis supports a diagnosis of allergy. Proof of sinus eosinophilia or basophilia by sinus smear or scraping May assistance the diagnosis also.

Role of this Antibody in other ailments

Many people are affected by seasonal allergic rhinitis and due to this Smooth Muscle Actin Antibody get responsible. Lots of people experience nasal congestion, runny nose, sneezing, itchy watery eyes and scratchy throat that characterize allergic rhinitis. Males and females are equally affected. Personal and family history of asthma and atopic dermatitis are risk factors for this condition. The symptoms of allergic rhinitis are provoked by allergens in the environment. When people have allergic rhinitis during particular seasons, such as the spring and fall, it is called seasonal allergic rhinitis. The typical allergens involved in SAR are pollens: trees in the spring, grass in the summer and weeds in the fall. Genetic predisposition and lifestyle habits such as inadequate physical activity, high fat diet, and high salt intake promote high blood pressure it has been also found that of adults in most countries suffer from hypertension. This problems do come genetically which are sourced through smooth muscle antibodies. Despite effective and relatively inexpensive treatment available, less than one out of four hypertensive individuals have their blood pressure controlled successfully this poor overall treatment success is mainly attributed to the symptomless nature of hypertension and the necessity for long-term treatment with currently available medications that require at least once daily self-administration.

Solution for these ailments

Vaccine against hypertension is an innovative treatment, injected every 4 - 6 months, to combat non-compliance. The pathogenesis of hypertension is multifactorial. Renin-angiotensin system is important system in the body that regulates blood pressure. And this is tested through this antibody. The most common cause is disruption of the Renin--angiotensin—aldosterone system (RAAS) and the first vaccine study was carried out against renin. While the vaccine reduced blood pressure in animal models, it also caused autoimmune disease. In the last decade, vaccines against angiotensin I, angiotensin II, and angiotensin II-type 1 receptors have demonstrated acceptable safety profiles in animal and human studies. Reduction in blood pressure can be achieved by inducing immunity against targets in the RAAS. The target antigen and selection of adjuvant are crucial factors determining effectiveness and safety of the vaccine. So behind every fatal disease the antibody researchers are doing their best o find solutions and get rid of these ailments.

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